As you know, eMule has been really successful , it could be compared to napster, everybody used it... until aMule appeared and offered an alternative.
aMule is based on eMule and offers a more simplified and structured interface, although the main options are practically the same.
The first thing we should emphasize is that it doesn't need to be installed, so it becomes a portable application. When we run aMule we find a very similar interface, although the settings and advanced options are grouped in a different way.
If you are not happy with your P2P client and you want to try soething new, give it a try. aMule works pretty well and promises you lots of files and top speed.